Sanders-Bush Lab >> Publications
Publications
Myers, RL, Airey, DC, Manier, DH, Shelton, RC and Sanders-Bush E. Polymorphisms in regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression. Biol Psychiat. May 11; [Epub ahead of print], 2006.
Hackler, EA, Airey, DC Shannon, CC Sodhi, MS and Sanders-Bush,E. 5-HT2C receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice, Neurosci Res. 55(1):96-104, 2006.
Bentzen EL, Tomlinson ID, Mason J, Gresch P, Warnement MR, Wright D, Sanders- Bush E, Blakely R, Rosenthal SJ. Surface modification to reduce nonspecific binding of quantum dots in live cell assays. Bioconjug Chem. 16(6):1488-94, 2005.
Sodhi MS, Airey D, Lambert W, Paul J. Harrison PJ, Burnet PWJ, and Sanders Bush E. A rapid new method to detect RNA editing reveals antipsychotic-induced changes in 5-HT2C transcripts. Mol. Pharmacol. 68: 711-719, Online publication May 25, 2005.
Fentress HM, Grinde E, Mazurkiewicz JE, Backstrom JR, Herrick-Davis K, and Sanders-Bush, E. Pharmacological properties of the Cys23Ser Single Nucleotide polymorphism in human 5-HT2C receptor isoforms. Pharmacogenomics J. 4:244-54, Online Publication, May 2005.
Gresch PJ, Smith RL, Barrett RJ, Sanders-Bush E. Behavioral Tolerance to Lysergic Acid Diethylamide is Associated with Reduced Serotonin-2A Receptor Signaling in Rat Cortex. Neuropsychopharmacology. 30: 1693-1702, Online Publication March 9, 2005
Akin, Demet, Hal Manier, D, Sanders-Bush, Elaine, Shelton, Richard C. Signal transduction abnormalities in melancholic depression. Int J Neuropsychopharmacol, 8(1), 5-16, 2005.
Benneyworth MA, Smith RL, Barrett RJ, Sanders-Bush E. Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice.
Psychopharmacology (Berl). 179(4):854-62, 2005..
Akin, Demet, Manier, D Hal, Sanders-Bush, Elaine, Shelton, Richard C. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology, 29(11), 2081-7, 2004.
Hazelwood, Lisa A, Sanders-Bush, Elaine. His452Tyr polymorphism in the human 5-HT2A receptor destabilizes the signaling conformation. Mol Pharmacol, 66(5), 1293-300, 2004.
McGrew, Lori, Price, Raymond D, Hackler, Elizabeth, Chang, Mike S S, Sanders-Bush, Elaine. RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA. Mol Pharmacol, 65(1), 252-6, 2004.
Nichols, Charles D, Sanders-Bush, Elaine. Molecular genetic responses to lysergic acid diethylamide include transcriptional activation of MAP kinase phosphatase-1, C/EBP-beta and ILAD-1, a novel gene with homology to arrestins. J Neurochem, 90(3), 576-84, 2004.
Sodhi, Monsheel S K, Sanders-Bush, Elaine. Serotonin and brain development. Int Rev Neurobiol, 59, 111-74, 2004.
Miner, L A H, Backstrom, J R, Sanders-Bush, E, Sesack, S R. Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex. Neuroscience, 116(1), 107-17, 2003.
Nichols, Charles D, Garcia, Efrain E, Sanders-Bush, Elaine. Dynamic changes in prefrontal cortex gene expression following lysergic acid diethylamide administration. Brain Res Mol Brain Res, 111(1-2), 182-8, 2003.
Parker, Lisan L, Backstrom, Jon R, Sanders-Bush, Elaine, Shieh, Bih-Hwa. Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1. J Biol Chem, 278(24), 21576-83, 2003.
Sanders-Bush, Elaine, Fentress, Hugh, Hazelwood, Lisa. Serotonin 5-ht2 receptors: molecular and genomic diversity. Mol Intervent, 3(6), 319-30, 2003.
Smith, Randy L, Barrett, Robert J, Sanders-Bush, Elaine. Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice. Psychopharmacology (Berl), 166(1), 61-8, 2003.
Gresch, P J, Strickland, L V, Sanders-Bush, E. Lysergic acid diethylamide-induced Fos expression in rat brain: role of serotonin-2A receptors. Neuroscience, 114(3), 707-13, 2002.
McGrew, L, Chang, M S S, Sanders-Bush, E. Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits. Mol Pharmacol, 62(6), 1339-43, 2002.
Nichols, C D, Ronesi, J, Pratt, W, Sanders-Bush, E. Hallucinogens and Drosophila: linking serotonin receptor activation to behavior. Neuroscience, 115(3), 979-84, 2002.
Nichols, Charles D, Sanders-Bush, Elaine. A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain. Neuropsychopharmacology, 26(5), 634-42, 2002.
Smith, Randy L, Gresch, Paul J, Barrett, Robert J, Sanders-Bush, Elaine. Stimulus generalization by fenfluramine in a quipazine-ketanserin drug discrimination is not dependent on indirect serotonin release. Pharmacol Biochem Behav, 72(1-2), 77-85, 2002.
Berg, K A, Cropper, J D, Niswender, C M, Sanders-Bush, E, Emeson, R B, Clarke, W P. RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity. Br J Pharmacol, 134(2), 386-92, 2001.
Bubser, M, Backstrom, J R, Sanders-Bush, E, Roth, B L, Deutch, A Y. Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum. Synapse, 39(4), 297-304, 2001.
Bubser, M., Backstrom, J.R., Sanders-Bush, E., Roth, B.L., and Deutch, A.Y. Distribution of serotonin 5-HT2A receptors in afferents of the rat striatum. Synapse, 39(4), 297-304, 2001.
Niswender, C M, Herrick-Davis, K, Dilley, G E, Meltzer, H Y, Overholser, J C, Stockmeier, C A, Emeson, R B, Sanders-Bush, E. RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology, 24(5), 478-91, 2001.
Niswender, C.M., Herrick-Davis, K., Dilley, G.E., Meltzer, H.Y., Overholser, J.C., Stockmeier, C.A., Emeson, R.B., and Sanders-Bush, E. RNA editing of the human serotonin 5- HT2C receptor: Alterations in suicide and implications for serotonergic pharmacology. Neuropsychopharmacology, 24, 478-491, 2001.
Peavey, R.D., Chang, M.S.S., Sanders-Bush, E. and Conn, P.J. Metabotropic glutamate receptor5- induced phosphorylation of extracellular signal regulated kinase in astrocytes depends on transactivation of epidermal growth factor. J. Neurosci., 21, 9619-28, 2001.
Peavy, R D, Chang, M S, Sanders-Bush, E, Conn, P J. Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor. J Neurosci, 21(24), 9619-28, 2001.
Price, R D, Weiner, D M, Chang, M S, Sanders-Bush, E. RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein. J Biol Chem, 276(48), 44663-8, 2001.
Price, R.D., Weiner, D.M., Chang, M.S.S., and Sanders-Bush, E. RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein. J. Biol. Chem., 276, 44663-44668, 2001.
Backstrom JR, Price RD, Reasoner DT and Sanders-Bush E. Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. J Biol Chem, 275, 23620-23626, 2000.
Backstrom, J R, Price, R D, Reasoner, D T, Sanders-Bush, E. Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. J Biol Chem, 275(31), 23620-6, 2000.
Chang M, Zhang L, Tam JP and Sanders-Bush E. Dissecting G-protein receptor signaling pathways with membrane permeable blocking peptides: Endogenous 5-HT2C receptors in choroid plexus epithelial cells. J Biol Chem, 275, 7021-7029, 2000.
Chang, M S, Tam, J P, Sanders-Bush, E. Dissecting intracellular signaling pathways with membrane-permeable peptides. Sci STKE, 2000(47), PL1, 2000.
Chang, M, Zhang, L, Tam, J P, Sanders-Bush, E. Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. J Biol Chem, 275(10), 7021-9, 2000.
Price, R D, Sanders-Bush, E. RNA editing of the human serotonin 5-HT(2C) receptor delays agonist-stimulated calcium release. Mol Pharmacol, 58(4), 859-62, 2000.
Price, R.D. and Sanders-Bush, E . RNA editing of the human serotonin 5-HT2C receptor delays agonist stimulated calcium release. Mol. Pharmacol, (58), 859-862, 2000.
Backstrom, J R, Chang, M S, Chu, H, Niswender, C M, Sanders-Bush, E. Agonist-directed signaling of serotonin 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD). Neuropsychopharmacology, 21(2 Suppl), 77S-81S, 1999.
Backstrom, J R, Chang, M S, Chu, H, Niswender, C M, Sanders-Bush, E. Agonist-Directed Signaling of Serotonin 5-HT(2C) Receptors: Differences Between Serotonin and Lysergic Acid Diethylamide (LSD). Neuropsychopharmacology, 21 Suppl 1, S77-81, 1999.
Backstrom, J.R., Chang, M.S., Chu, H., Niswender, C.M. and Sanders-Bush, E. Agonist-directed signaling of serotonin 5-HT2C receptors: Differences between serotonin and lysergic acid diethylamide (LSD). Neuropsychopharmacology, 21(25), 77S-81S, 1999.
Bancila, M, Vergé, D, Rampin, O, Backstrom, J R, Sanders-Bush, E, McKenna, K E, Marson, L, Calas, A, Giuliano, F. 5-Hydroxytryptamine2C receptors on spinal neurons controlling penile erection in the rat. Neuroscience, 92(4), 1523-37, 1999.
Grotewiel, M S, Sanders-Bush, E. Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression. Naunyn Schmiedebergs Arch Pharmacol, 359(1), 21-7, 1999.
Grotewiel, M.S. And Sanders-Bush, E. Differences in agonist-independent activity of 5-HT2A , and 5-HT2C receptors revealed by heterologous expression. Naunyn-Schmiedeberg?s Arch. Pharmacol., 359(1), 21-27, 1999.
Niswender CM, Copeland SC, Herrick-Davis K, Emeson RB and Sanders-Bush E. RNA editing of the human serotonin 5- hydroxytryptamine2C receptor silences constitutive activity. J Biol Chem , 274, 9472-9478, 1999.
Niswender, C M, Copeland, S C, Herrick-Davis, K, Emeson, R B, Sanders-Bush, E. RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. J Biol Chem, 274(14), 9472-8, 1999.
Smith RL, Barrett RJ and Sanders-Bush E. Mechanism of tolerance development to DOI: Down-regulationof 5-HT2A, but not 5-HT2C, receptors . Psychopharmacology, 144, 248-254, 1999.
Smith, R L, Barrett, R J, Sanders-Bush, E. Mechanism of tolerance development to 2,5-dimethoxy-4-iodoamphetamine in rats: down-regulation of the 5-HT2A, but not 5-HT2C, receptor. Psychopharmacology (Berl), 144(3), 248-54, 1999.
Willins, D L, Berry, S A, Alsayegh, L, Backstrom, J R, Sanders-Bush, E, Friedman, L, Roth, B L. Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience, 91(2), 599-606, 1999.
Willins, D.L., Berry, S.A., Alsayegh, L., Backstrom, J.R., Sanders-Bush, E., Friedman, L., Roth, B.L. Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience , 91(2), 599-606, 1999.
Niswender, C M, Sanders-Bush, E, Emeson, R B. Identification and characterization of RNA editing events within the 5-HT2C receptor. Ann N Y Acad Sci, 861, 38-48, 1998.
Niswender, C.M., Sanders-Bush, E., and Emeson, R.B. Identification and characterization of RNA editing events within the serotonin 2creceptor. Ann. N.Y. Acad. Sci., 861, 38-48, 1998.
Seifert, R, Wenzel-Seifert, K, Lee, T W, Gether, U, Sanders-Bush, E, Kobilka, B K. Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor. J Biol Chem, 273(18), 5109-16, 1998.
Seifert, R, Wenzel-Seifert, K, Lee, T W, Gether, U, Sanders-Bush, E, Kobilka, B K. Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor. J Biol Chem, 273(9), 5109-16, 1998.
Seifert, R., Wenzel-Seifert, K., Lee, T.W., Gether, U., Sanders-Bush, E. And Kobolka, B.K. Different effects of GS alpha splice variants on beta 2-adrenoreceptor-mediated signalling. The beta2-adrenoreceptor coupled to the long splice variant of GS aplha has properties of a constitutively active receptor. J. Biol. Chem., 273, 5109-5116, 1998.
Smith, R L, Canton, H, Barrett, R J, Sanders-Bush, E. Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors. Pharmacol Biochem Behav, 61(3), 323-30, 1998.
Smith, R.L., Canton, H., Barrett, R.J., and Sanders-Bush. E Agonist properties of N, N-dimethyltryptamine at serotonin 5-HT2A , and 5-HT2C, receptors. Pharmacol. Biochem. Behav., 61(3), 343-330, 1998.
Willins, D L, Alsayegh, L, Berry, S A, Backstrom, J R, Sanders-Bush, E, Friedman, L, Khan, N, Roth, B L. Serotonergic antagonist effects on trafficking of serotonin 5-HT2A receptors in vitro and in vivo. Ann N Y Acad Sci, 861, 121-7, 1998.
Backstrom, J R, Sanders-Bush, E. Generation of anti-peptide antibodies against serotonin 5-HT2A and 5-HT2C receptors. J Neurosci Methods, 77(1), 109-17, 1997.
Backstrom, J.R. And Sanders-Bush, E. Generation of anti-peptide antibodies against serotonin 5-HT 2a and 5- HT2C receptors. Journal of Neuroscience Methodology , 77(1), 109-117, 1997.
Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E and Emeson RB. Regulation of serotonin2C receptor G-protein coupling by RNA editing. Nature , 387, 303-308, 1997.
Burns, C M, Chu, H, Rueter, S M, Hutchinson, L K, Canton, H, Sanders-Bush, E, Emeson, R B. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature, 387(6630), 303-8, 1997.
Gether, U, Ballesteros, J A, Seifert, R, Sanders-Bush, E, Weinstein, H, Kobilka, B K. Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. J Biol Chem, 272(5), 2587-90, 1997.
Gether, U., Ballestros, J.A., Seifert, R., Sanders-Bush, E., Weinstein, H., and Kobilka, B.K. Structural instability of a constitutively active G-protein-coupled receptor. Agonist-independent activation due to conformational flexiblility. J.Biol. Chem. , 272, 2587-2590, 1997.
Monte, A P, Waldman, S R, Marona-Lewicka, D, Wainscott, D B, Nelson, D L, Sanders-Bush, E, Nichols, D E. Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives. J Med Chem, 40(19), 2997-3008, 1997.
Canton, H, Emeson, R B, Barker, E L, Backstrom, J R, Lu, J T, Chang, M S, Sanders-Bush, E. Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. Mol Pharmacol, 50(4), 799-807, 1996.
Canton, H., Emeson, R.B., Barker, E.L., Backstrom, J.R., Lu, J.T., Chang, M.S., and Sanders-Bush, E. Identifica- tion, molecular cloning, and distribution of a short variant of the serotonin 5-HT2C receptor produced by alternative splicing. Mol. Pharmacol., 50, 199-807, 1996.
Westphal, R S, Sanders-Bush, E. Differences in agonist-independent and -dependent 5-hydroxytryptamine2C receptor-mediated cell division. Mol Pharmacol, 49(3), 474-80, 1996.
Westphal, R.S., Sanders-Bush, E. Differences in agononist-independent and agonist-dependent 5-HT2c receptor mediated cell division. Mol. Pharmacol., 49, 474-480, 1996.
Backstrom, J R, Westphal, R S, Canton, H, Sanders-Bush, E. Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. Brain Res Mol Brain Res, 33(2), 311-8, 1995.
Ike, J, Canton, H, Sanders-Bush, E. Developmental switch in the hippocampal serotonin receptor linked to phosphoinositide hydrolysis. Brain Res, 678(1-2), 49-54, 1995.
Monte, A P, Marona-Lewicka, D, Kanthasamy, A, Sanders-Bush, E, Nichols, D E. Stereoselective LSD-like activity in a series of d-lysergic acid amides of (R)- and (S)-2-aminoalkanes. J Med Chem, 38(6), 958-66, 1995.
Onaivi, E S, Bishop-Robinson, C, Darmani, N A, Sanders-Bush, E. Behavioral effects of (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze test. Life Sci, 57(26), 2455-66, 1995.
Sanders-Bush E, Canton H. Serotonin receptors: Signal transduction pathways. Psychopharmacology: Fourth Generation of Progress, , , 1995.
Smith, R L, Barrett, R J, Sanders-Bush, E. Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor. J Pharmacol Exp Ther, 275(2), 1050-7, 1995.
Smith, R.L., Barrett, R.J., Sanders-Bush, E. Neurochemical and behavioral evidence that quipazine ketanserin discrimination is mediated by serotonin2A receptors. J. Pharmacol. Exp. Therap., 275, 1050-1057, 1995.
Westphal, R S, Backstrom, J R, Sanders-Bush, E. Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization. Mol Pharmacol, 48(2), 200-5, 1995.
Westphal, R.S., Backstrom, J.R., Sanders-Bush, E. Increased basal phosphorylation of the constitutively active serotonin2c receptor accompanies agonist-mediated desensitization. Mol. Phannacol., 48, 200-205, 1995.
Barker, E L, Westphal, R S, Schmidt, D, Sanders-Bush, E. Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. J Biol Chem, 269(16), 11687-90, 1994.
Barker, E.L., Westphal, R.S., Schmidt, D., Sanders-Bush, E. Constitutively active 5HT2c receptors reveal novel inverse agonist activity of receptor ligands. J. Biol. Chem., 269, 11687-11690, 1994.
Grotewiel, M S, Chu, H, Sanders-Bush, E. m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts. J Pharmacol Exp Ther, 271(2), 1122-6, 1994.
Grotewiel, M S, Sanders-Bush, E. Regulation of serotonin2A receptors in heterologous expression systems. J Neurochem, 63(4), 1255-60, 1994.
Grotewiel, M.S., Sanders-Bush, E. Regulation of serotonin 5HT2A receptors in heterologous expression systems. J. Neurochem., 63, 1255-1260, 1994.
Mayer, S E, Sanders-Bush, E. 5-Hydroxytryptamine type 2A and 2C receptors linked to Na+/K+/Cl- cotransport. Mol Pharmacol, 45(5), 991-6, 1994.
Sanders-Bush, E. Neurochemical evidence that hallucinogenic drugs are 5-HT1c receptor agonists: what next. NIDA Res Monogr, 146, 203-13, 1994.
Westphal, R S, Sanders-Bush, E. Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists. Mol Pharmacol, 46(5), 937-42, 1994.
Westphal, R.S., Sanders-Bush, E. Reciprocal binding properties of 5-HT2c receptor agonists and inverse agonists. Mol. Pharmacol., 46, 937-942, 1994.
Barker EL, Sanders-Bush E. 5HT1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane, Mol.Pharm., 1993; 44:725-730, 1993.
Barker, E L, Sanders-Bush, E. 5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Mol Pharmacol, 44(4), 725-30, 1993.
Mayer, S E, Sanders-Bush, E. Sodium-dependent antiporters in choroid plexus epithelial cultures from rabbit. J Neurochem, 60(4), 1308-16, 1993.
Mayer, S.E., Sanders-Bush, E. Sodium-dependent antiporters in choroid plexus epithelial cultures from rabbit. J. Neurochem, 60, 1308-1316, 1993.
Burris, K D, Sanders-Bush, E. Unsurmountable antagonism of brain 5-hydroxytryptamine2 receptors by (+)-lysergic acid diethylamide and bromo-lysergic acid diethylamide. Mol Pharmacol, 42(5), 826-30, 1992.
Burris, K.D., Sanders-Bush, E. Unsurmountable antagonism of brain 5HT2 receptors by (+)lysergic acid diethylamide (LSD) and bromo-LSD . Mol. Pharmacol., 42, 826-830, 1992.
Esterle, T M, Sanders-Bush, E. Serotonin agonists increase transferrin levels via activation of 5-HT1C receptors in choroid plexus epithelium. J Neurosci, 12(12), 4775-82, 1992.
Esterle, T.M., Sanders-Bush, E. Serotonin agonists increase transferrin levels via activation of serotonin 5HT1C receptor in choroid plexus epithelium. J. Neurosci., 12(12), 4775-4785, 1992.
Glennon, R A, Teitler, M, Sanders-Bush, E. Hallucinogens and serotonergic mechanisms. NIDA Res Monogr, 119, 131-5, 1992.
Barker, E L, Burris, K D, Sanders-Bush, E. Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Res, 552(2), 330-2, 1991.
Barker, E.L., Burris, K.D., Sanders-Bush, E. Phosphoinositide hydrolysis linked 5HT2 receptors in fibroblasts from choroid plexus . Brain Res., 552, 330-332, 1991.
Burris, K D, Breeding, M, Sanders-Bush, E. (+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist. J Pharmacol Exp Ther, 258(3), 891-6, 1991.
Burris, K.D., Breeding, M., Sanders-Bush, E. (+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist. J. Phrmacol. Exp. Therap., 258, 891-896, 1991.
Esterle, T M, Sanders-Bush, E. From neurotransmitter to gene: identifying the missing links. Trends Pharmacol Sci, 12(10), 375-9, 1991.
Sanders-Bush, E. From neurotransmitter to gene-identifying the missing links . TIPS, 12, 375-379, 1991.
Sanders-Bush, E, Breeding, M. Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs. Psychopharmacology (Berl), 105(3), 340-6, 1991.
Sanders-Bush E, Breeding M. Serotonin1C receptor reserve in choroid plexus masks receptor subsensitivity. J. Pharmacol. Exp. Therap., 252, 984-988, 1990.
Sanders-Bush, E. Adaptive regulation of central serotonin receptors linked to phosphoinositide hydrolysis. Neuropsychopharmacology, 3(5-6), 411-6, 1990.
Sanders-Bush, E, Breeding, M. Serotonin1c receptor reserve in choroid plexus masks receptor subsensitivity. J Pharmacol Exp Ther, 252(3), 984-8, 1990.
Sanders-Bush, E, Tsutsumi, M, Burris, K D. Serotonin receptors and phosphatidylinositol turnover. Ann N Y Acad Sci, 600, 224-35; discussion 235-6, 1990.
Sanders-Bush, E. Tsutsumi, M., Burris, K.D. Serotonin receptors and phosphatidylinositol turnover. Ann. N.Y. Acad. Sci., 600, 244-236, 1990.
Smith, R L, Barrett, R J, Sanders-Bush, E. Adaptation of brain 5HT2 receptors after mianserin treatment: receptor sensitivity, not receptor binding, more accurately correlates with behavior. J Pharmacol Exp Ther, 254(2), 484-8, 1990.
Smith, R.L., Barrett, R.J., Sanders-Bush, E. Adaptation of brain 5HT2 receptors after mianserin treatment: Receptor sensitivity, not receptor binding, correlates with behavior . J. Pharmacol. Exp. Therap., 254, 484-488, 1990.
Tsutsumi, M, Sanders-Bush, E. 5-HT-induced transferrin production by choroid plexus epithelial cells in culture: role of 5-HT1c receptor. J Pharmacol Exp Ther, 254(1), 253-7, 1990.
Sanders-Bush, E, Breeding, M, Knoth, K, Tsutsumi, M. Sertraline-induced desensitization of the serotonin 5HT-2 receptor transmembrane signaling system. Psychopharmacology (Berl), 99(1), 64-9, 1989.
Tsutsumi, M, Skinner, M K, Sanders-Bush, E. Transferrin gene expression and synthesis by cultured choroid plexus epithelial cells. Regulation by serotonin and cyclic adenosine 3',5'-monophosphate. J Biol Chem, 264(16), 9626-31, 1989.
Tsutsumi, M., Skinner, M.K., Sanders-Bush, E. transferrin gene expression and synthesis by cultured choroid plexus epithelial cells: Regulation by serotonin and cyclic 3',5'-adenosin monophosphate . J. Biol.Chem. , 264, 9626-9631, 1989.
Gillespie, D D, Manier, D H, Sanders-Bush, E, Sulser, F. The serotonin/norepinephrine-link in brain. II. Role of serotonin in the regulation of beta adrenoceptors in the low agonist affinity conformation. J Pharmacol Exp Ther, 244(1), 154-9, 1988.
Sanders-Bush, E, Breeding, M. Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus. J Pharmacol Exp Ther, 247(1), 169-73, 1988.
Sanders-Bush, E, Burris, K D, Knoth, K. Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis. J Pharmacol Exp Ther, 246(3), 924-8, 1988.
Sanders-Bush, E. and Breeding, M. Putative selective 5HT-2 antagonists block serotonin 5HT-1c receptors in the choroid plexus. J. Pharmacol. Exp. Therap., 247, 169-173, 1988.
Sanders-Bush, E., Burris, K.D. and Knoth, K. Lysergic acid diethylamide and 2,5-dimethoxy-4 methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis. J. Pharmacol. Exp. Therap., 246, 924-928, 1988.
Conn, P J, Janowsky, A, Sanders-Bush, E. Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus. Brain Res, 400(2), 396-8, 1987.
Conn, P J, Sanders-Bush, E. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther, 242(2), 552-7, 1987.
Conn, P J, Sanders-Bush, E. Central serotonin receptors: effector systems, physiological roles and regulation. Psychopharmacology (Berl), 92(3), 267-77, 1987.
Manier, D H, Gillespie, D D, Sanders-Bush, E, Sulser, F. The serotonin/noradrenaline-link in brain. I. The role of noradrenaline and serotonin in the regulation of density and function of beta adrenoceptors and its alteration by desipramine. Naunyn Schmiedebergs Arch Pharmacol, 335(2), 109-14, 1987.
Sanders-Bush, E, Breeding, M, Roznoski, M. 5HT2 binding sites after mianserin: comparison of loss of sites and brain levels of drug. Eur J Pharmacol, 133(2), 199-204, 1987.
Sulser, F, Sanders-Bush, E. The serotonin-norepinephrine link hypothesis of affective disorders: receptor-receptor interactions in brain. Adv Exp Med Biol, 221, 489-502, 1987.
Blackshear, M A, Martin, L L, Sanders-Bush, E. Adaptive changes in the 5-HT2 binding site after chronic administration of agonists and antagonists. Neuropharmacology, 25(11), 1267-71, 1986.
Conn, P J, Sanders-Bush, E. Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site. J Neurosci, 6(12), 3669-75, 1986.
Conn, P J, Sanders-Bush, E. Biochemical characterization of serotonin stimulated phosphoinositide turnover. Life Sci, 38(7), 663-9, 1986.
Conn, P J, Sanders-Bush, E. Agonist-induced phosphoinositide hydrolysis in choroid plexus. J Neurochem, 47(6), 1754-60, 1986.
Conn, P J, Sanders-Bush, E, Hoffman, B J, Hartig, P R. A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proc Natl Acad Sci U S A, 83(11), 4086-8, 1986.
Conn, P.J., Sanders-Bush, E., Hoffman, B.J. and Hartig, P.R., A. A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proc. Natl. Acad. Sci., 83, 4086-4088, 1986.
Sanders-Bush, E, Conn, P J. Effector systems coupled to serotonin receptors in brain: serotonin stimulated phosphoinositide hydrolysis. Psychopharmacol Bull, 22(3), 829-36, 1986.
Conn, P J, Sanders-Bush, E. Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions. J Pharmacol Exp Ther, 234(1), 195-203, 1985.
Sanders-Bush, E, Conn, J, Sulser, F. The serotonin/norepinephrine-linked beta-adrenoceptor system and the mode of action of antidepressants. Psychopharmacol Bull, 21(3), 373-8, 1985.
Conn, P J, Sanders-Bush, E. Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex. Neuropharmacology, 23(8), 993-6, 1984.
Friedman, R L, Barrett, R J, Sanders-Bush, E. Discriminative stimulus properties of quipazine: mediation by serotonin2 binding sites. J Pharmacol Exp Ther, 228(3), 628-35, 1984.
Friedman, R L, Sanders-Bush, E, Barrett, R L. Clozapine blocks disruptive and discriminative stimulus effects of quipazine. Eur J Pharmacol, 106(1), 191-3, 1984.
Blackshear, M A, Friedman, R L, Sanders-Bush, E. Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites. Naunyn Schmiedebergs Arch Pharmacol, 324(2), 125-9, 1983.
Friedman, R, Barrett, R J, Sanders-Bush, E. Additional evidence that L-5-hydroxytryptophan discrimination models a unique serotonin receptor. Psychopharmacology (Berl), 80(3), 209-13, 1983.
Barrett, R J, Blackshear, M A, Sanders-Bush, E. Discriminative stimulus properties of L-5-hydroxytryptophan: behavioral evidence for multiple serotonin receptors. Psychopharmacology (Berl), 76(1), 29-35, 1982.
Blackshear, M A, Sanders-Bush, E. Serotonin receptor sensitivity after acute and chronic treatment with mianserin. J Pharmacol Exp Ther, 221(2), 303-8, 1982.
Martin, L L, Sanders-Bush, E. Comparison of the pharmacological characteristics of 5 HT1 and 5 HT2 binding sites with those of serotonin autoreceptors which modulate serotonin release. Naunyn Schmiedebergs Arch Pharmacol, 321(3), 165-70, 1982.
Martin, L L, Sanders-Bush, E. The serotonin autoreceptor: antagonism by quipazine. Neuropharmacology, 21(5), 445-50, 1982.
Sanders-Bush, E. Regulation of serotonin storage and release. Adv Biochem Psychopharmacol, 34, 17-34, 1982.
Blackshear, M A, Steranka, L R, Sanders-Bush, E. Multiple serotonin receptors: regional distribution and effect of Raphe lesions. Eur J Pharmacol, 76(4), 325-34, 1981.
Bush, M T, Sanders-Bush, E. Diazomethane: improved analytical and distillation techniques for small quantities and some synthetic applications. Anal Biochem, 106(2), 351-62, 1980.
Steranka, L R, Sanders-Bush, E. Long-term effects of continuous exposure to amphetamine on brain dopamine concentration and synaptosomal uptake in mice. Eur J Pharmacol, 65(4), 439-43, 1980.
Mobley, P L, Sanders-Bush, E, Smith, H E, Sulser, F. Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: role of its hydroxylated metabolites. Naunyn Schmiedebergs Arch Pharmacol, 306(3), 267-73, 1979.
Steranka, L R, Sanders-Bush, E. Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neurons. Biochem Pharmacol, 28(20), 3103-7, 1979.
Steranka, L R, Sanders-Bush, E. Long-term effects of fenfluramine on central serotonergic mechanisms. Neuropharmacology, 18(11), 895-903, 1979.
Massari, V J, Tizabi, Y, Sanders-Bush, E. Evaluation of the neurotoxic effects of p-chloroamphetamine: a histological and biochemical study. Neuropharmacology, 17(7), 541-8, 1978.
Sanders-Bush, E, Steranka, L R. Immediate and long-term effects of p-chloroamphetamine on brain amines. Ann N Y Acad Sci, 305, 208-21, 1978.
Steranka, L R, Sanders-Bush, E. Long-term reduction of brain serotonin by p-chloroamphetamine: effects of inducers and inhibitors of drug metabolism. J Pharmacol Exp Ther, 206(2), 460-7, 1978.
Steranka, L R, Sanders-Bush, E. Long-term effects of continuous exposure to p-chloroamphetamine on central serotonergic mechanisms in mice. Biochem Pharmacol, 27(16), 2033-7, 1978.
El-Yousef, M K, Steranka, L, Sanders-Bush, E. Rapid tolerance to the motor effects of p-chloroamphetamine in rats. Psychopharmacology (Berl), 55(2), 109-14, 1977.
Sanders-Bush, E, Massari, V J. Actions of drugs that deplete serotonin. Fed Proc, 36(8), 2149-53, 1977.
Steranka, L R, Barrett, R J, Sanders-Bush, E. Facilitation of Sidman avoidance performance by p-chloroamphetamine: role of biogenic amines. Neuropharmacology, 16(11), 751-9, 1977.
Steranka, L R, Sanders-Bush, E, Barrett, R J. Tolerance to p-chloroamphetamines effects on Sidman avoidance performance and catecholamine metabolism. Neuropharmacology, 16(11), 761-9, 1977.
Steranka, L, Bessent, R, Sanders-Bush, E. Reversible and irreversible effects of p-chloroamphetamine on brain serotonin in mice. Commun Psychopharmacol, 1(5), 447-54, 1977.
Steranka, L, Sanders-Bush, E. Temporal effects of p-chloroamphetamine on catecholamine synthesis. Eur J Pharmacol, 45(1), 83-6, 1977.
Sanders-Bush, E. Long-term effects of para-chloroamphetamine on central serotonergic mechanisms. Psychopharmacol Bull, 12(3), 57-9, 1976.
Sanders-Bush, E, Oates, J A, Bush, M T. Metabolism of bufotenine-2'-14C in human volunteers. Life Sci, 19(9), 1407-11, 1976.
Gallager, D W, Sanders-Bush, E, Aghajanian, G K, Sulser, F. An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain Res, 93(1), 111-22, 1975.
Massari, V J, Sanders-Bush, E. Synaptosomal uptake and levels of serotonin in rat brain areas after p-chloroamphetamine or B-9 lesions. Eur J Pharmacol, 33(2), 419-22, 1975.
Sanders-Bush, E, Bushing, J A, Sulser, F. Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms. J Pharmacol Exp Ther, 192(1), 33-41, 1975.
Sekerke, H J, Smith, H E, Bushing, J A, Sanders-Bush, E. Correlation between brain levels and biochemical effects of the optical isomers of p-chloroamphetamine. J Pharmacol Exp Ther, 193(3), 835-44, 1975.
Sanders-Bush, E, Gallager, D A, Sulser, F. On the mechanism of brain 5-hydroxytryptamine depletion by p-chloroamphetamine and related drugs and the specificity of their action. Adv Biochem Psychopharmacol, 10, 185-94, 1974.
Schaefer, G J, Barrett, R J, Sanders-Bush, E, Vorhees, C V. p-Chloroamphetamine: evidence against a serotonin mediated learning deficit in PKU. Pharmacol Biochem Behav, 2(6), 783-9, 1974.
Smith, H E, Burrows, E P, Miano, J D, Mount, C D, Sanders-Bush, E, Sulser, F. Action of (S)-and(R)-para-substituted amphetamine hydrochlorides and (alphaS)-and (alphaR)-p-chloronorephedrine and (alphaS)-and (alphaR)-p-chloronorpseudoephedrine hydrochlorides on the level of 5-hydroxytryptamine and the activity of tryptophan hydroxylase in rat brain. J Med Chem, 17(4), 416-21, 1974.
Yarbrough, G G, Buxbaum, D M, Sanders-Bush, E. Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration. J Pharmacol Exp Ther, 185(2), 328-35, 1973.
Gallager, D W, Sanders-Bush, E, Sulser, F. Dissociation between behavioral effects and changes in metabolism of cerebral serotonin following 9 -tetrahydrocannabinol. Psychopharmacologia, 26(4), 337-45, 1972.
Sanders-Bush, E, Bushing, J A, Sulser, F. p-Chloroamphetamine--inhibition of cerebral tryptophan hydroxylase. Biochem Pharmacol, 21(10), 1501-10, 1972.
Sanders-Bush, E, Bushing, J A, Sulser, F. Long-term effects of p-chloroamphetamine on tryptophan hydroxylase activity and on the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in brain. Eur J Pharmacol, 20(3), 385-8, 1972.
Miller, K W, Sanders-Bush, E, Dingell, J V. p-Chloramphetamine--species differences in the rate of disappearance and the lowering of cerebral serotonin. Biochem Pharmacol, 20(2), 500-3, 1971.
Schmidt, M J, Sanders-Bush, E. Tryptophan hydroxylase activity in developing rat brain. J Neurochem, 18(12), 2549-51, 1971.
Sulser, F, Sanders-Bush, E. Effect of drugs on amines in the CNS. Annu Rev Pharmacol, 11, 209-30, 1971.
Yarbrough, G G, Buxbaum, D M, Sanders-Bush, E. Increased serotonin turnover in the acutely morphine treated rat. Life Sci I, 10(17), 977-83, 1971.
Sanders-Bush, E, Sulser, F. P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin. J Pharmacol Exp Ther, 175(2), 419-26, 1970.
Strada, S J, Sanders-Bush, E, Sulser, F. p-Chloroamphetamine. Temporal relationship between psychomotor stimulation and metabolism of brain norepinephrine. Biochem Pharmacol, 19(9), 2621-9, 1970.