Deanna G. Adams, Ph.D.

Postdoctoral Research Fellow

Vanderbilt University Medical Center
Department of Pharmacology
428 Robinson Research Building
Nashville, TN 37232-6600
Lab: 615.322.3285
Fax: 615.343.6532

E-mail: deanna.adams@vanderbilt.edu

 
 

Project Title:


Identification of interacting proteins and substrates for PP2A holoenzymes

 

Education:  

B.S. Biology 

University of Arizona, Tucson, AZ

1994 

Ph.D. Pharmacology & Toxicology 

University of Arizona, Tucson, AZ

2002 

 

Publications:

1. Adams, D. G., Coffee Jr., R.L., Zhong, H., Pelech, S., Strack, S., and Wadzinski, B.E. Positive Regulation of Raf1-MEK1/2-ERK1/2 Signaling by Protein-Serine-Threonine Phosphatase 2A Holoenzymes (submitted 2005).

2. Codreanu, S.G., Adams, D. G., Wadzinski, B.E., and Liebler, D.C. Alkylation Stress Triggers Decrease in Enzymatic Activity of Protein Phosphatase 2A (in preparation 2005).

3. Adams, D. G., and Wadzinski, B.E. Isolation and Characterization of PP2A Holoenzymes Containing FLAG-tagged B Subunits. Invited Chapter, Method. Mol. Bio. (in press 2005).

4. Fritz, A., Brayer, K.J., McCormick, N., Adams, D. G., Wadzinski, B.E., and Vaillancourt, R.R. Phosphorylation of Serine 526 is Required for MEKK3 Activity and Dephosphorylation is Blocked by 14-3-3. (in preparation 2005)

5. Adams, D. G., Sachs, N.A., and Vaillancourt R.R. Phosphorylation of the Stress-Activated Protein Kinase, MEKK3 at Serine 166. Arch. Biochem. Biophys. 2002 Nov; 407 (1):103-116.

6.Tran, N.L., Adams, D. G., and Vaillancourt, R.R. Signal Transduction from N-cadherin Increases Bcl-2. Regulation of the PI3- kinase/Akt pathway by homophilic adhesion and actin cytoskeleton organization. J. Biol. Chem. 2002; 277: 32905-32914.

7. Levan, T.D., Bloom, J.W., Adams, D. G., and Halonen M. Platelet-Activating Factor Induction of Activator Protein-1 Signaling in Bronchial Epithelial Cells. Mol Pharmacol 1998; Jan, 53(1):135-140. 

Awards and Honors: 

Pharmaceutical Research and Manufacturers of America Foundation

Predoctoral Fellowship

2000-2002

College of Pharmacy, Caldwell Health Sciences Predoctoral Fellowship 2000
University of Arizona, Center for Toxicology Flinn Fellowship 1997-1999
University of Arizona Undergrad Biology Research Program 1992-1994